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Marker for Prognosis and Drug Resistance of Ewing's Sarcoma
Summary: Researchers at the University of Utah are working to develop methods for early detection and improved treatment of Ewing's sarcoma. They have identified glutathione-S-transferase M4 (GSTM4) as a critical target gene in this cancer. GSTM4 contributes to tumorigenesis and drug resistance in Ewing's sarcoma. Patients with higher levels...
Published: 5/2/2019
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Inventor(s):
Stephen Lessnick
,
Wen Luo
Keywords(s):
Category(s):
Diagnostics
,
Biomarkers
Biomarker for Improved Diagnosis of Ewing’s Sarcoma
Invention SummaryEwing’s sarcoma is a highly aggressive bone or soft tissue-associated tumor of children and young adults. The tumor frequently progresses undetected until it metastasizes, whereupon the mortality of the disease greatly increases. This technology reveals a new molecular marker, NKX2.2, which has high specificity and sensitivity...
Published: 8/13/2019
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Inventor(s):
Stephen Lessnick
Keywords(s):
Category(s):
Diagnostics
,
Biomarkers
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