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Improved Mass Spectrometry Assay for Measurement of Thyroglobulin

Invention SummaryMeasurement of thyroglobulin is used to monitor patients after treatment for differentiated thyroid carcinoma. After total thyroidectomy and radioactive ablation, serum concentrations of thyroglobulin should decrease to very low levels. A rise of serum concentration of thyroglobulin is indicative of cancer recurrence. In about 30%...

Published: 3/21/2019 | Inventor(s): Mark Kushnir, Alan Rockwood, A. Wayne Meikle

Keywords(s):

Category(s): Diagnostics, Biomarkers

Sensitive LC-MS/MS Assay for 5a-Dihydrotestosterone and Other Analytes

Invention Summary Measurement of testosterone and other androgens has many clinical applications. Measurement of serum androgens is important in adult, geriatric, pediatric endocrinology, and oncology patients. Immunoassays for androgens are often inaccurate due to analytical interferences, and measurement results often overestimate the true concentration,...

Published: 5/2/2019 | Inventor(s): Bingfang Yue, Alan Rockwood, Mark Kushnir, A. Wayne Meikle

Keywords(s):

Category(s): Diagnostics, Biomarkers