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Synthesis of Eight-Membered Heterocyclic Structures

Invention SummaryAn inventor at the University of Utah has developed a new method for the preparation of eight-membered N-heterocycles. When azetidinones and diynes are subjected to catalytic amounts of a Ni-complex, facile coupling occurs to afford high yields of azocine products, a structure that is prevalent in numerous pharmaceuticals.Value PropositionThe...

Published: 5/22/2019 | Inventor(s): Janis Louie, Puneet Kumar

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Category(s): Biotechnology, Proteomics