Search Results - proteomics

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Benzonorbornadiene Derivatives and Reactions Thereof

Technology / Product SummaryThis technology is a set of reactions relating to benzonorbornadiene derivatives and tetrazine. The purpose of this reaction is to create a "bioorthogonal reaction" that will release a particular cargo molecule within cells. These bioorthogonal reactions are designed to take place without interfering with the...

Published: 9/13/2019 | Inventor(s): Raphael Franzini

Keywords(s): Biotechnology, Proteomics

Category(s): Biotechnology, Proteomics

Novel Mucoadhesive, Long Lasting, Site-Specific Progesterone Delivery Gel

Invention SummaryThe present invention is a novel glycol-chitin-based bioadhesive drug delivery composition for progesterone for convenient, safe, effective and site-specific delivery. Progesterone (P4) is used as part of the conservative management for endometrial hyperplasia (EH), which may progress to or coexist with endometrial carcinoma. Due to...

Published: 9/24/2019 | Inventor(s): Margit (maggie) Janat-Amsbury, Kang Moo Huh, Aliyah Almomen, Sungpil Cho, C. Matthew Peterson

Keywords(s): Biotechnology, Proteomics

Category(s): Biotechnology, Proteomics

New collagen targeting and imaging strategy

Collagen Mimetic Peptide (CMP) – Targeting and Imaging Collagen ChainsUniversity Reference Number: U-5752 Invention SummaryA new reagent that specifically targets collagen chains, ideal for detecting damaged collagens associated with pathologic conditions such as tumor, arthritis, fibrosis, osteoporosis, and other wounds. When used with minimally...

Published: 2/20/2020 | Inventor(s): Michael Yu, Yang Li, Martin Pomper, Catherine Foss, Allen Wang, Daniel Ho

Keywords(s): Biotechnology, Proteomics

Category(s): Biotechnology, Proteomics

Synthesis of Eight-Membered Heterocyclic Structures

Invention SummaryAn inventor at the University of Utah has developed a new method for the preparation of eight-membered N-heterocycles. When azetidinones and diynes are subjected to catalytic amounts of a Ni-complex, facile coupling occurs to afford high yields of azocine products, a structure that is prevalent in numerous pharmaceuticals.Value PropositionThe...

Published: 5/22/2019 | Inventor(s): Janis Louie, Puneet Kumar

Keywords(s):

Category(s): Biotechnology, Proteomics

Stable Perfluorocarbon Emulsion for Tissue Engineering Applications

Optimized Perfluorocarbon Emulsion for Tissue EngineeringUniversity Reference Number: U-4556Invention SummaryPerfluorocarbon (PFC) emulsions have been used as oxygen carriers in blood substitutes since World War II. Currently, droplets in PFC emulsions gradually coalesce to form larger droplets undermining long-term applications in tissue engineering....

Published: 8/8/2019 | Inventor(s): Natalya Rapoport, Glenn Prestwich, Russell Morris Condie

Keywords(s):

Category(s): Biotechnology, Proteomics

Method of T Lymphocyte Generation From Hematopoietic Stem Cells

Summary: This technology includes methods for the production of T lymphocytes and Cytotoxic (Natural Killer, or NK) lymphocytes from uncommitted hematopoietic stem/progenitor cells. It begins with undifferentiated hematopoetic stem cells, cultured under conditions which promote specification of the lymphocyte lineage. These cells subsequently...

Published: 5/2/2019 | Inventor(s): Gerald Spangrude, Birgitta Mitchell

Keywords(s): Cancer Diagnostics and Treatment, Non-Cancer Disease Therapeutics, Stem Cells

Category(s): Biotechnology, Proteomics

Highly Potent Bryostatin Analogues Prepared Using a Pyran Annulation Process

Invention Description: Bryostatin 1 has been shown to act synergistically in combination with other chemotherapeutic agents to modulate protein kinase C (PKC) activity, with a potent anti-leukemic effect and action against lung, prostate and non-Hodgkin's lymphoma tumor cells. Despite this promise, no readily renewable supply of bryostatin 1 exists,...

Published: 8/14/2019 | Inventor(s): Gary Keck, Matthew Kraft, Anh Truong, Carina Sanchez, Wei Li, Jonathan Covel, Dennie Welch, Yam Poudel

Keywords(s):

Category(s): Biotechnology, Proteomics