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Highly Potent Bryostatin Analogues Prepared Using a Pyran Annulation Process
Invention Description: Bryostatin 1 has been shown to act synergistically in combination with other chemotherapeutic agents to modulate protein kinase C (PKC) activity, with a potent anti-leukemic effect and action against lung, prostate and non-Hodgkin's lymphoma tumor cells. Despite this promise, no readily renewable supply of bryostatin 1 exists,...
Published: 8/14/2019
|
Inventor(s):
Gary Keck
,
Matthew Kraft
,
Anh Truong
,
Carina Sanchez
,
Wei Li
,
Jonathan Covel
,
Dennie Welch
,
Yam Poudel
Keywords(s):
Category(s):
Biotechnology
,
Proteomics
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