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Cholesterol and Oligoarginine Complex for siRNA Delivery
Agent Delivered / Target: siRNA / endocytosis capitalizing on cholesterol and cell-penetrating peptides Chemical Composition: Cholesterol oligo-D-arginine (Chol-R9) Physical Composition: Complexes of siRNA and Chol-R9 Intellectual Property / Development: US patent 7,740,880 issued / in vivo in mice
Published: 10/1/2019
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Inventor(s):
Won Jong Kim
,
Sung Wan Kim
Keywords(s):
Cancer Diagnostics and Treatment
,
Cell Lines
,
Medical Devices
,
Research Tools & Reagents
Category(s):
Research Tools & Reagents
,
Cell Lines
In Vitro Production of Natural Killer Cells and Creation of Immortalized Natural Killer
Cell Lines
Invention Description: Natural Killer (NK) cells provide early defense against pathogens several days before the adaptive immune responses become operational. They are a type of lymphocyte responsible for destroying viruses and tumor cells. An NK cell kills a target cell by releasing perforin (and other molecules) which damages the target cell...
Published: 5/7/2019
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Inventor(s):
Schickwann Tsai
Keywords(s):
Category(s):
Research Tools & Reagents
,
Cell Lines
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