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Naonparticle Antibody Conjugate Platform For Targeted Delivery and Tumor Killing

Invention SummaryMonoclonal antibody as a single agent therapy for solid and blood cancers show limited clinical efficacy. High doses are needed which result in undesired adverse immunogenicity and toxicity. Conjugating antibodies to cytotoxic drug show durable clinical response. However ADC designing is complex, with knowledge of linkers, drug and...

Published: 9/13/2019 | Inventor(s): Xinjian Chen, Chengke Luo

Keywords(s): Biologics, Therapeutics

Category(s): Therapeutics, Biologics