Search Results - hamidreza+ghandehari

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Invention SummaryThis invention is a unique gelling protein polymer that can transition from liquid to solid state at physiological temperatures. The gelling polymer is composed of genetically engineered silk-elastin like protein polymers (SELP) which have repeating amino acid sequences of silk and elastin proteins. The sequence is optimized for liquid-to-solid...

Published: 8/30/2019 | Inventor(s): Joseph Cappello, Hamidreza Ghandehari, Azadeh Poursaid

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Category(s): Medical Devices, Orthopedics

Radiation Enhanced Macromolecular Delivery of Therapeutic Agents for Chemotherapy

Invention Description: This invention aims to develop novel polymeric delivery systems that significantly enhance the therapeutic index of cancer chemotherapy. Water soluble macromolecules are conjugated to dual anticancer drugs that have unmet clinical needs such as acquired drug resistance, toxicity or poor solubility. The polymer conjugates of...

Published: 7/11/2019 | Inventor(s): Abhijit Ray, Hamidreza Ghandehari

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Category(s): Oncology, Drug Delivery, Radiology, Therapeutics

Targeted Combination Drug Delivery and Photothermal Therapy for the Treatment of Cancer (this can be potentially used for other diseases as well)

Invention Description: Gold nanorods have great potential to treat cancer by photothermal therapy. Local heat generated by high energy laser excitation of their surface plasmons has the capacity to kill malignancies by photothermal lysis of nearby cancerous cells. Unfortunately, limited tissue penetration depths of light may ultimately limit the...

Published: 6/6/2019 | Inventor(s): Hamidreza Ghandehari, Adam Gormley, Abhijit Ray

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Category(s): Drug Delivery, Platform Method, Therapeutics, Radiology