Search Results - animal+models

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Highly Characterized, Clinically Relevant Tumorgrafts as Models of Breast Cancer

Technology Summary: University of Utah researchers have generated the first publicly available collection of orthotopic breast tumorgrafts. These novel models for breast tumor growth and metastasis are in the form of highly characterized, transplantable tumors derived from patients, engrafted directly into the mammary glands of mice. The technique...

Published: 5/7/2019 | Inventor(s): Alana Welm, Yoko Derose, Yi-Chun Lin

Keywords(s):

Category(s): Research Tools & Reagents, Animal Models

A Mouse Model of Synovial Sarcoma

Invention Summary: The present invention provides the first and only genetic mouse model of synovial sarcoma, a highly aggressive, malignant childhood/young adult soft tissue cancer. This mouse model was generated by conditionally expressing the human SYT-SSX2 fusion protein with myoblasts. It faithfully recapitulates human synovial sarcoma in presentation,...

Published: 7/10/2019 | Inventor(s): Malay Haldar, Mario Capecchi

Keywords(s):

Category(s): Research Tools & Reagents, Animal Models