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Invention Summary: The present invention provides the first and only genetic mouse model of synovial sarcoma, a highly aggressive, malignant childhood/young adult soft tissue cancer. This mouse model was generated by conditionally expressing the human SYT-SSX2 fusion protein with myoblasts. It faithfully recapitulates human synovial sarcoma in presentation,...

Published: 7/10/2019 | Inventor(s): Malay Haldar, Mario Capecchi

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Category(s): Research Tools & Reagents, Animal Models