Search Results - christof+westenfelder

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Methods for Treatment and Prevention of Acute Renal Failure and Multi-organ Failure

Invention Summary Acute Renal Failure (ARF), in the context of multi-organ failure and in high risk patients, remains a common, and often fatal (~50% mortality), complication. Preventative measures are only poorly effective, and dialysis therapy is expensive and time consuming. ARF is characterized by cell injury and death by necrosis and apoptosis...

Published: 7/17/2019 | Inventor(s): Christof Westenfelder

Keywords(s): Non-Cancer Disease Therapeutics

Category(s): Therapeutics, Drug Repurposing

Methods for In Vivo Stimulation of Erythropoietin Production

Summary: This invention discloses an approach whereby the administration of a synthetic organic compound specifically induces proliferation of erythropoietin-producing peritubular interstitial cells in the kidney, which results in increased synthesis of erythropoietin. After cessation of treatment with the synthetic compound, there is persistence...

Published: 10/1/2019 | Inventor(s): Bellamkonda Kishore, Jorge Isaac, Christof Westenfelder

Keywords(s): Biologics, Non-Cancer Disease Therapeutics, Therapeutics

Category(s): Therapeutics, Biologics