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Peptide - Polymer Complex Delivers Nucleic Acid to the Artery Wall **Value Express**

Patent Abstract An artery wall binding peptide (AWBP) based on the artery wall cell-binding domain of apolipoprotein B-100 was conjugated to a cationic backbone configured for forming a complex with a nucleic acid to produce a composition that enhances gene transfer to artery wall cells. An illustrative cationic backbone is poly(ethylene glycol)-grafted-poly(L-lysine)...

Published: 7/19/2019 | Inventor(s): Sung Wan Kim, Lei Yu, Jae-Woon Nah

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Category(s): Therapeutics, Gene Therapy, Silencing & Editing, Research Tools & Reagents