Search Results - molecular

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Genetic Marker Detection for Chronic Fatigue

Invention SummaryU-6096 allows for the detection of Myalgic Encephalomyelitis, more commonly known as Chronic Fatigue Syndrome (CFS). At present, there are no accurate means of distinguishing this disorder from various conditions such as depression, which can make diagnosis and treatment difficult. Through the use of genetic testing, this methodology...

Published: 11/2/2017 | Inventor(s): Kathleen Light, Alan Light, Ronald Hughen, Andrea White, Lucinda Bateman

Keywords(s):

Category(s): Diagnostics, Molecular

Novel Primer Design for Quantitative Allele-Specific PCR

Invention SummaryThis invention provides a novel primer design, incorporating site-specific mismatches and locked nucleic acids, for real-time quantitative allele-specific PCR (AS-PCR), resulting in improved sensitivity, specificity and reproducibility of detection. This method provides greatly improved quantitation of low-level polymorphisms and alleles,...

Published: 1/29/2020 | Inventor(s): Josef Prchal, Roberto Nussenzweig, Sabina Swierczek

Keywords(s): Diagnostics, Molecular, Nucleic Acid Diagnostics

Category(s): Diagnostics, Molecular

SCN9A is Mutated in Familial and Sporadic Febrile Convulsions

Invention Summary: Febrile seizures are the most common seizure disorder of infancy with a prevalence of 2-5% in European and North American infants. The impact of seizures brought on by elevated body temperature is considerable because individuals who experience them have a 2-7% incidence of developing afebrile seizures and epilepsy later in life....

Published: 8/7/2019 | Inventor(s): Mark Leppert, Nanda Singh

Keywords(s):

Category(s): Diagnostics, Molecular