Search Results - nucleic+acid+diagnostics

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Rapid Nanoparticle-based DNA SequencingUniversity Reference Number: U-4813 Invention SummaryThis technology is a new method for tagging and imaging short nucleic acid chains using selective hybridization of heterogeneous gold nanoparticles and scanning electron microscopy. In particular, each base pair is tagged with a different size gold nanoparticle...

Published: 10/24/2014 | Inventor(s): Carlos Mastrangelo, Renny Fernandez

Keywords(s): Nucleic Acid Diagnostics, Omics, Research Tools

Category(s): Nanotechnology, Diagnostics

Small Molecule Detection Assay in Biological Systems

Small Molecule Detection Assay in Biological SystemsUniversity Reference Number: U-5091Invention SummaryA University of Utah inventor developed a novel small molecule detection platform based on nucleic acid aptamers capable of selectively detecting drugs, toxins or metabolites in complex biological systems. The key aspect of the platform is the development...

Published: 8/5/2019 | Inventor(s): Jennifer Heemstra

Keywords(s): Nucleic Acid Diagnostics

Category(s): Diagnostics, Assay Platforms

Novel Primer Design for Quantitative Allele-Specific PCR

Invention SummaryThis invention provides a novel primer design, incorporating site-specific mismatches and locked nucleic acids, for real-time quantitative allele-specific PCR (AS-PCR), resulting in improved sensitivity, specificity and reproducibility of detection. This method provides greatly improved quantitation of low-level polymorphisms and alleles,...

Published: 1/29/2020 | Inventor(s): Josef Prchal, Roberto Nussenzweig, Sabina Swierczek

Keywords(s): Diagnostics, Molecular, Nucleic Acid Diagnostics

Category(s): Diagnostics, Molecular