Search Results - research+tools

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Rapid Nanoparticle-based DNA SequencingUniversity Reference Number: U-4813 Invention SummaryThis technology is a new method for tagging and imaging short nucleic acid chains using selective hybridization of heterogeneous gold nanoparticles and scanning electron microscopy. In particular, each base pair is tagged with a different size gold nanoparticle...

Published: 10/24/2014 | Inventor(s): Carlos Mastrangelo, Renny Fernandez

Keywords(s): Nucleic Acid Diagnostics, Omics, Research Tools

Category(s): Nanotechnology, Diagnostics

H+-gated Ion Channel

Invention SummaryThe nematode Caenorhabditis elegans is a powerful research tool in understanding neuromotor control. Researchers at the University of Utah have identified genes that encode a component of a heteromultimeric H+-gated ion channel that is required for posterior body contractions in C. elegans. Characterization of this channel provided...

Published: 8/8/2019 | Inventor(s): Erik Jorgensen, Asim Beg, Paola Nix

Keywords(s): Research Tools

Category(s): Biotechnology, Genomics

Consensus-Based Scoring Algorithm for a Computer Screen-Based PALS Simulator

Invention Summary: Adapting medical simulation technology to allow on-demand access to high-quality training in managing pediatric arrests will depend on developing more cost-effective ways of providing realistic simulations and meaningful performance assessments to a large number of providers across geographic areas covered by hospital networks....

Published: 10/2/2019 | Inventor(s): Kathleen Ventre

Keywords(s): Computer Software, Computing, Medical Devices, Research Tools, Simulation & Modeling

Category(s): Computing, Simulation & Modeling

Penumbra Nucleic Acid Molecules, Proteins and Methods of Their Detection and Use, Especially for Myeloid (Bone Marrow) Diseases

Invention Description: This invention identifies the human Penumbra gene nucleic acid molecules, proteins encoded by these nucleic acid molecules, antibodies raised against these proteins, and inhibitors of these proteins. The invention also includes methods of using these molecules in the detection of disease, including human myeloid malignancies....

Published: 5/7/2019 | Inventor(s): Schickwann Tsai, Zhong Chen

Keywords(s): Non-Cancer Disease Therapeutics, Research Tools

Category(s): Research Tools & Reagents, Reagents

Tumor Environment Induced Ligand Expressing Nanocarrier System

Invention Description: Cancer cells are often characterized by specific antigens or overexpressed receptors on cell surfaces. Such receptors provide uptake routes for nutrients and signals from the surrounding environment, essential for active growth of the cells. These processes have now been utilized as an important delivery mode for macromolecular...

Published: 10/8/2019 | Inventor(s): You Han Bae, Kun Na, Eun Seong Lee

Keywords(s): Cancer Diagnostics and Treatment, Drug Delivery, Medical Devices, Nanotechnology, Research Tools, Therapeutics

Category(s): Therapeutics, Drug Delivery

SmedDb: A Dynamic Database for the Analysis, Integration and Hypothesis Testing of Spatio-Temporal Gene Expression Patterns

Invention Description: The present invention provides a Unix-based database for genome-wide DNA sequence queries. Schmidtea mediterranea database (SmedDb; http://planaria.neuro.utah.edu), is a molecular resource for studying platyhelminthes, stem cells and regeneration. SmedDb is a depository of immunohistological data, and nucleotide sequences...

Published: 3/15/2019 | Inventor(s): Alejandro Sanchez, Sofia Robb

Keywords(s): Research Tools

Category(s): Software, Research Tools & Reagents

Micro-Electric Impedance Tomography: Visualizing Particles and Biological Materials

Invention Summary: Novel technology, including a technique, hardware and software, has been developed to measure the size, shape and dielectric properties of the interior of a cell/particle and/or cell membrane. This device is based on measurements of current and voltage using a ring of electrodes around the outside of the cell/particle. The approach...

Published: 4/30/2019 | Inventor(s): Richard Rabbitt, Sameera Dharia

Keywords(s): Computer Hardware, Computer Software, Medical Devices, Research Tools

Category(s): Research Tools & Reagents, Instrumentation

Quantitative Analysis of Unresolved Isomers and Isobars by Tandem Mass Spectrometry

Summary: Tandem mass spectrometry is attractive for many applications due to its high selectivity, wide dynamic range, and high throughput capabilities. Analysis of isobars and isomers by tandem mass spectrometry is complicated by the similarity between their mass spectra and often requires extensive chromatographic separation in order to eliminate...

Published: 8/23/2019 | Inventor(s): Mark Kushnir, Alan Rockwood, Gordon Nelson

Keywords(s): Computer Software, Non-Cancer Disease Diagnostics, Research Tools

Category(s): Diagnostics, Assay Platforms

A Cross-flow Split-thin-flow cell

Invention Description: This technology describes a new high speed cross-flow split-thin-flow-cell separation microsystem. This new technique takes a cross flow as the major driving force for efficient separation/purification of a sample compared to already existing devices and techniques. The unique integration of cross flow allows continuous purification...

Published: 9/6/2018 | Inventor(s): Bruce Gale, Himanshu Sant, Venu Madhav Arremsetty, Srinivas Merugu

Keywords(s): Materials and Mining, Mechanical Engineering, Medical Devices, Research Tools

Category(s): Research Tools & Reagents, Microfluidics