Search Results - small+molecule

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New Potent ß-Catenin/T-cell Factor Inhibitors

Invention Summary New potent inhibitors of the ß-catenin/T-cell factor (Tcf) interaction have been designed and synthesized by a University of Utah inventor. These new micro molar inhibitors are shown to bind to key ß-catenin binding sights and are effective at preventing the growth of cancer cells. Value Proposition • New potent inhibitors,...

Published: 10/21/2019 | Inventor(s): Haitao (mark) Ji, Binxun Yu, Min Zhang, Wenxing Guo

Keywords(s): Small Molecule, Therapeutics

Category(s): Therapeutics, Small Molecule

Isolation, Identification and Uses of Antifungal Compounds

TECHNOLOGY SUMMARY New antifungal peptides called Burkholdines Can be used to treat fungal infections in human subjectsCan help solve deadly fungal infections in plants and crops which are resistant to existing antifungal agentsBENEFITSBurkholdine compounds are more potent than existing antifungal agents16-60 times the potency of amphotericin control...

Published: 9/13/2019 | Inventor(s): Eric Schmidt, Peter Jeffs, Joseph Falkinham

Keywords(s): Small Molecule, Therapeutics

Category(s): Therapeutics, Small Molecule

Novel Therapeutic Approaches for the Treatment of Acquired Nephrogenic Diabetes Insipidus

Summary: This invention discloses a novel set of interactions between the prostaglandin and purine signaling pathways that reveal a new class of drug targets for future NDI therapies. Market Applications: Nephrogenic Diabetes Insipidus (NDI) can be acquired as a result of the use of medicines such as lithium for bipolar disorders, or others such...

Published: 10/1/2019 | Inventor(s): Bellamkonda Kishore, Noel Carlson, Donald Kohan, Raoul Nelson

Keywords(s): Non-Cancer Disease Therapeutics, Small Molecule, Therapeutics

Category(s): Therapeutics, Small Molecule