Search Results - vicente+planelles

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Drug Family With The Ability to Reactivate Latent HIV

Invention SummaryAlthough current therapies can reduce HIV to undetectable levels, latent HIV virus continues to persist in hidden reservoirs within resting memory T cells. Once a patient stops the antiretroviral regimen, the latent virus will rebound in a matter of weeks.University of Utah investigators have identified specific compounds which are...

Published: 5/7/2019 | Inventor(s): Vicente Planelles, Alberto Bosque Pardos, Chris Ireland, Ryan Van Wagoner, Mary Kay Harper-Ireland, John Alan Maschek

Keywords(s):

Category(s): Therapeutics, Small Molecule

A Novel Ex vivo Model to Study Viral Latency

Invention SummaryAlthough current retroviral therapies can reduce HIV to undetectable levels, latent HIV virus continues to persist in hidden reservoirs within resting memory T cells. These reservoirs are widely recognized as a key obstacle which must be overcome to achieve a cure. Once a patient stops the antiretroviral regimen, the latent virus...

Published: 8/23/2019 | Inventor(s): Vicente Planelles, Alberto Bosque

Keywords(s):

Category(s): Research Tools & Reagents, Screening Assays